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Fuzzy Models of Differential Diagnosis of Pyelonephritis in Pregnant Women

Abstract

Purpose of the research is to improve the quality indicators of differential diagnosis of pyelonephritis in pregnant women while reducing the decision-making time by reducing the dimension of the feature space.

Methods. Differential diagnosis of such forms of pathology of pregnant women as serous pyelonephritis, purulent pyelonephritis and its transitional form belongs to the class of poorly formalized tasks. Exploratory analysis of the data structure presented by the urological department of the Kursk BSMP showed that according to the criteria of decision -making time-diagnostic quality, preference should be given to the method of synthesis of hybrid fuzzy models, combining the logic of L. Zadeh and E. Shortlif. At the same time, for a reliable diagnosis, it is enough to use data on the immune status of pregnant women.

Results. Using the chosen synthesis method, a system of fuzzy decision rules is obtained that combines E. Shortlif's iterative rules with the functions of belonging to the studied forms of pyelonephritis. Mathematical modeling and statistical tests of the obtained decision rules showed that in terms of the immune status, the diagnostic sensitivity, specificity and effectiveness in the classification of serous, purulent and intermediate forms of pyelonephritis exceed the level of 0.9.

Conclusion. In the course of research, it was found that for the differential diagnosis of forms of pyelonephritis in pregnant women by indicators of immune status, hybrid fuzzy models should be used with the aggregation of iterative models for assessing confidence in decisions made with membership functions. The obtained hybrid models have diagnostic sensitivity, specificity, and effectiveness higher than 0.9, which allows improving the quality of medical services provided to pregnant women with acute forms of pyelonephritis.

About the Authors

S. P. Seregin
Southwest State University
Russian Federation

Stanislav P. Seregin, Dr. of Sci. (Medical), Professor, Department of Biomedical Engineering

50 Let Oktyabrya str. 94, Kursk 305040



D. S. Rodionov
Southwest State University
Russian Federation

Dmitry S. Rodionov, Post-Graduate Student of the Department of Biomedical Engineering

50 Let Oktyabrya str. 94, Kursk 305040



I. M. Kholimenko
Kursk Regional Clinical Hospital of Emergency Medical Care
Russian Federation

Ivan M. Kholimenko, Urologist, Kursk City Clinical Hospital of Emergency Medical Care

45a Sumskaya str., Kursk 305007



L. P. Lazurina
Kursk State Medical University 3 K. Marksa str., Kursk 305041
Russian Federation

Lyudmila P. Lazurina, Dr. of Sci. (Biological), Head of the Department of Biological and Chemical Technology, Professor

3 K. Marksa str., Kursk 305041



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For citations:


Seregin S.P., Rodionov D.S., Kholimenko I.M., Lazurina L.P. Fuzzy Models of Differential Diagnosis of Pyelonephritis in Pregnant Women. Proceedings of the Southwest State University. Series: IT Management, Computer Science, Computer Engineering. Medical Equipment Engineering. 2021;11(1):98-111. (In Russ.)

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