Development of the Structure of a Generator of Superlowintensity Microwave Biomodulated Radiations for Experimental Medical-Biological Research

The purpose of research is to develop a microwave device-a new ultra-low intensity radiation in the range of 1 GHz and a power of <10 MW, designed for conducting biomedical experimental studies.

Methods. The scientific work was carried out by a translational group of researchers, including doctors, biologists, engineers, radiophysicists and programmers. In the materials of the article, the structure of the microwave generation module of the device, the structure and the circuit diagram of the timer of the device are considered. The reasons for the choice of biomodulation frequencies are given on the basis of the fundamental principles of chronobiology, taking into account the cyclic processes of cell functioning, namely, the elongation of the protein synthesis chain, microcirculation rhythms, the work of the thermoregulation center, near-hourly cycles of cell division and RNA synthesis.

Results. Based on the conducted research, the structure of a low-frequency biomodulator has been developed and presented. The functioning of the device is provided by the developed program code of the microcontroller. The developed mock-up sample of the device was tested using the spectrum and signal analyzer of the German company: ROHDE & SCHVARZ FSV SIGNAL ANALYZER 5 kHz 40 GHz. The sig-nal taken from the frame antenna of the device had a frequency of 1000 MHz with a signal quality of 100 kHz.

Conclusions. The positive effect of the effect of ultra-low intensity microwave radiation on mesenchymal stem cells (MSCs) is shown. A significant increase in the intensity of MSCS fluorescence in the mode of low-frequency biomodulation was revealed.

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