Decision support system for prediction and diagnosis of endometritis in the postpartum period
https://doi.org/10.21869/2223-1536-2025-15-3-181-200
Abstract
The purpose of the research is to develop a decision support system for gynecologists, based on synthesized prognostic and diagnostic decision rules, which will be used in the diagnosis and prognosis of postpartum endometritis.
Methods. The following tools were used in the development of the decision support system: medical statistics, expert system development methods, decision theory, and pattern recognition methods. Such tools for statistical data analysis as Excel and Statistica were used to process and analyze medical data, as well as to verify crucial diagnostic rules. To assess the risk of postpartum endometritis and its diagnosis, 31 signs are included, ranked according to their degree of informativeness. These data were used as the basis for the development of an algorithm for predicting the risk of developing postpartum endometritis in a decision support system.
Results. The application of the developed diagnostic decision rules on clinically representative material showed a diagnostic effectiveness of 0,96±0,02. The developed expert system can be effectively applied in clinical conditions. It is also possible to use this expert system in the educational process when training medical professionals.
Conclusion. Consideration of risk factors, integration of data from various sources, the use of prognostic models and the formation of individual recommendations for treatment and prevention are all key aspects that should be taken into account when developing such a system. The introduction of such a system into clinical practice can significantly improve the quality of diagnosis and treatment of postpartum endometritis, reduce the risk of complications and improve patient outcomes.
About the Authors
V. V. AksenovRussian Federation
Vitaliy V. Aksenov, Head of Laboratories of the Department of Biomedical Engineering
50 Let Oktyabrya Str. 94, Kursk 305040
S. P. Seregin
Russian Federation
Stanislav P. Seregin, Doctor of Sciences (Medical), Professor, Head of the Department of Biomedical Engineering
50 Let Oktyabrya Str. 94, Kursk 305040
S. A. Gromiko
Russian Federation
Svetlana A. Gromyko, Student of the Department of Biomedical Engineering
50 Let Oktyabrya Str. 94, Kursk 305040
S. V. Petrov
Russian Federation
Sergey V. Petrov, Candidate of Sciences (Medical), Obstetrician-Gynecologist, Head
114 Pavlunovsky Str., Kursk 305040
A. V. Khardikov
Russian Federation
Aleksandr V. Khardikov, Doctor of Sciences (Medical), Obstetrician-Gynecologist, Associate Professor of the Department of Obstetrics and Gynecology
114 Pavlunovsky Str., Kursk 305040; 3 K. Marx Str., Kursk 305041
A. S. Petrova
Russian Federation
Arina S. Petrova, Student
3 K. Marx Str., Kursk 305041
References
1. Neretin A.A., Petrovsky S.A. Medical expert decision support systems for clinical syndromes. In: Nauchno-tekhnicheskii progress: aktual'nye i perspektivnye napravleniya budushche-go: sbornik materialov IX Mezhdunarodnoi nauchno-prakticheskoi konferentsii, 28 noyabrya 2018 g. = Scientific and technological progress: current and promising areas of the future: Collection of materials of the IX International Scientific and Practical Conference, 28 November 2018. Vol. 2. Kemerovo: ZapSibNTs; 2018. P. 106–108. (In Russ.)
2. Dobrovolsky I.I., Artemenko M.V., Marentsov M.V. Features of synthesis of decisive rules for medical a smart of expert systems. In: Korenevsky N.A. (ed.). Mediko-ekologicheskie informatsionnye tekhnologii: sbornik nauchnykh statei po materialam XKhII Mezhdunarodnoi nauchno-tekhnicheskoi konferentsii = Medical and environmental information technologies: collection of scientific articles on the materials of the XXII International Scientific and Technical Conference. Kursk: Yugo-Zapadnyi gosudarstvennyi universitet; 2019. P. 63–71. (In Russ.)
3. Yakunchenko T.I., Seregin S.P., Shulga L.V., Knysh O.A., Siplivy G.V., Shmarova D.R. Creation of mathematical models using multidimensional regression analysis for diabetic retinopathy screening. Sistemnyi analiz i upravlenie v biomeditsinskikh sistemakh = System Analysis and Management in Biomedical Systems. 2024;23(4):200–205. (In Russ.) https://doi.org/10.36622/1682-6523.2024.23.4.025
4. Agarkov N.M., Golovchenko O.V., Aksenov V.V., et al. Improving the diagnosis of acute endometritis based on modeling and cluster analysis of local immunity parameters. Klinicheskaya laboratornaya diagnostika = Clinical Laboratory Diagnostics. 2018;63(4):239– 242. https://doi.org/10.18821/0869-2084-2018-63-4-239-242
5. Aksenov V.V. Diagnosis and classification of patients with acute endometritis based on discriminant analysis and informative diagnostic symptoms. Izvestiya Yugo-Zapadnogo gosudarstvennogo universiteta. Seriya: Upravlenie, vychislitel'naya tekhnika, informatika. Meditsinskoe priborostroenie = Proceedings of the Southwest State University. Series: Control, Computer Engineering, Information Science. Medical Instruments Engineering. 2015;4(17):93–98. (In Russ.)
6. Agarkov N.M., Tkachenko P.V., Aksenov V.V., et al. Rationalization of the differential diagnosis of ovarian cancer and chronic salpingoophoritis according to the parameters of disintegration and network modeling of changes in blood flow in the uterine and ovarian arteries and veins. Voprosy onkologii = Issues of Oncology. 2017; 63(5):766–769. (In Russ.) https://doi.org/10.37469/0507-3758-2017-63-5-766-769
7. Agarkov N.M., Makkonen K.F., Aksenov V.V., et al. The use of flow cytometry and diagnostically significant indicators of systemic cellular immunity for the diagnosis of acute endometritis. Klinicheskaya laboratornaya diagnostika = Clinical Laboratory Diagnostics. 2017;62(9):563–567. (In Russ.) https://doi.org/10.18821/0869-2084-2017-62-9-563-567
8. Agarkov N.M., Agarkova V.N., Aksenov V.V., et al. Rationalization of laboratory diagnostics of acute salpingoophoritis according to informative parameters of humoral immunity. Klinicheskaya laboratornaya diagnostika = Clinical Laboratory Diagnostics. 2017;62(11):690–693. (In Russ.) https://doi.org/10.18821/0869-2084-2017-62-11-690-693
9. Shutkin A.N., Boitsova E.A., Korenevskaya S.N., Provotorov V.Ya. Assessment of the functional state and state of human health using the theory of measurement of latent variables based on G. Rush models. Sistemnyi analiz i upravlenie v biomeditsinskikh sistemakh = System Analysis and Management in Biomedical Systems. 2014;13(4):927–932. (In Russ.) https://doi.org/10.21869/2223-1536-2023-13-3-102-121
10. Konenevsky N.A., Rodionova S.N., Khripina I.I., Myasoedova M.A. Hybrid fuzzy models for assessing the functional state and health of a human operator of information-rich systems. Sistemnyi analiz i upravlenie v biomeditsinskikh sistemakh = Systems Analysis and Management in Biomedical Systems. 2019;18(2):105–116. (In Russ.) https://doi.org/10.25987/VSTU.2019.18.2.017
11. Bykov A.V., Rodionova S. N., Parkhomenko S. A., Starodubtseva L. V., Khripina I.I. Forecasting the appearance and development of gangrene of the lower extremities using fuzzy intelligent technologies. Kursk: Izdatel'skii dom VIP; 2017. 420 c. (In Russ.)
12. Al-Kasasbeh R.T., Korenevsky N.A., Aikeyeva A.A., Shaqadan A.A., Maksim I., Rodionova S.N. Developing a biotech scheme using fuzzy logic model to predict the occurrence of diseases using a person's functional state. International Journal of Computer Applications in Technology. 2020;62(3):257–267. https://doi.org/10.1504/IJCAT.2020.106570
13. Korenevsky N.A., Rodionova S.N., Khripina I.I. Methodology of synthesis of hybrid fuzzy decision rules for medical intelligent decision support systems. Stary Oskol: TNT; 2019. 472 p. (In Russ.)
14. Artemenko M.V., Fedyanin V.I., Shutkin A.N., Kvashnina G.A. Expert system for assessing the risk of occurrence and development of thromboembolism. Integrativnye tendentsii v meditsine i obrazovanii = Integrative Trends in Medicine and Education. 2024;4:9– 16. (In Russ.)
15. Korenevsky N.A., Aksyonov V.V., Rodionova S.N., Gontarev S.N., Lazurina L.P., Safronov R.I. A method of complex assessment of the level of informativeness of classification features in conditions of a fuzzy data structure. Izvestiya Yugo-Zapadnogo gosudarstvennogo universiteta. Seriya: Upravlenie, vychislitel'naya tekhnika, informatika. Meditsinskoe priborostroenie = Proceedings of the Southwest State University. Series: Control, Computer Engineering, Information Science. Medical Instruments Engineering. 2022;12(3):80–96. (In Russ.) https://doi.org/10.21869/2223-1536-2022-12-3-80-96
16. Safronov R.I., Razumova K.V., Rybakov A.Yu., Lyakh A.V. Synthesis of models for forecasting and diagnosing occupational diseases based on hybrid fuzzy technology. Izvestiya Yugo-Zapadnogo gosudarstvennogo universiteta. Seriya: Upravlenie, vychislitel'naya tekhnika, informatika. Meditsinskoe priborostroenie = Proceedings of the Southwest State University. Series: Control, Computer Engineering, Information Science. Medical Instruments Engineering. 2023;13(3):102–121. (In Russ.) https://doi.org/10.21869/2223-1536-2023-13-3-102-121
17. Novikov A.V., Seregin S.P., Shestakov S.G., Shatokhin M.N. Antioxidant status and the state of local immunity in patients with chronic prostatitis. Chelovek i ego zdorov'e = Man and His Health. 2001;(2):50–53. (In Russ.)
18. Korenevskiy N.A., Bykov A.V., Al-Kasasbeh R.T., Alshamasin M.S., Rodionova S.N., Maksim I., Parkhomenko S.A., Al-Smadi M.M., Al-Jundi M., Aikeyeva A.A. Fuzzy models of choice of prevention schemes for the occurrence and development of gangrene of the lower extremities. Critical Reviews in Biomedical Engineering. 2021;49(5):1–12. https://doi.org/10.1615/CritRevBiomedEng.2022038502
19. Korenevsky N. A., Rodionova S. N., Razumova K. V., Lukash O. Yu. Assessment of the protective functions of the body and its systems by indicators of functional state and functional reserve. Sistemnyi analiz i upravlenie v biomeditsinskikh sistemakh = System Analysis and Management in Biomedical Systems. 2023;22(3):67–77. (In Russ.) https://doi.org/10.36622/VSTU.2023.22.3.009
20. Grigorov I.Y., Starodubtseva L.V., Seregin S.P., Shulga L.V. Forecasting and early diagnosis of bronchial asthma in workers specializing in argon welding based on fuzzy mathematical models. Izvestiya Yugo-Zapadnogo gosudarstvennogo universiteta. Seriya: Upravlenie, vychislitel'naya tekhnika, informatika. Meditsinskoe priborostroenie = Proceedings of the Southwest State University. Series: Control, Computer Engineering, Information Science. Medical Instruments Engineering. 2023;13(2):170–183. (In Russ.) https://doi.org/10.21869/2223-1536-2023-13-2-170-183
Review
For citations:
Aksenov V.V., Seregin S.P., Gromiko S.A., Petrov S.V., Khardikov A.V., Petrova A.S. Decision support system for prediction and diagnosis of endometritis in the postpartum period. Proceedings of the Southwest State University. Series: IT Management, Computer Science, Computer Engineering. Medical Equipment Engineering. 2025;15(3):181-200. (In Russ.) https://doi.org/10.21869/2223-1536-2025-15-3-181-200


